Nektar

Nektar Reports Phase 2b Proof-of-Concept for Rezpegaldesleukin in Severe Alopecia Areata

December 17, 2025 /

Nektar Therapeutics has announced topline results from its Phase 2b REZOLVE-AA trial evaluating rezpegaldesleukin (REZPEG) in patients with severe-to-very-severe alopecia areata (AA). The data establish clinical proof of concept and support advancement into Phase 3 development, positioning rezpegaldesleukin as a potential non-JAK option for this autoimmune hair-loss condition. What is Rezpegaldesleukin? Rezpegaldesleukin is a first-in-class…

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