Drug WAY-316606 To Move Ahead With Pharma Company

The Guardian has reported the intriguing drug WAY-316606, which was originally developed for osteoporosis, may soon be entering human hair growth clinical trials with the help of an Italian pharmaceutical company.

I was pleasantly surprised to find some worthwhile information in the latest “mainstream media baldness cure” article published by The Guardian today. I should also add I enjoyed reading the Guardian’s article and I thought it was a well done piece. The write-up detailed background information on the discovery of WAY-316606’s potential role in hair growth. If you remember back in May 2018, the drug made headlines after researchers Drs. Nathan Hawkshaw and Ralf Paus of Manchester University published a scientific article about WAY’s effect on inhibiting the SFRP1 protein to induce hair growth. The team had been researching the drug cyclosporine A (CsA) with the intention of uncovering the secret to its hair growth effect. Hawkshaw and Paus figured, if they could identify the mechanism of action that causes CsA to grow hair, and then duplicate that action without the other potential side effects that come with cyclosporine A, they would have a winner on their hands. That potential “winner” would prove to be WAY-316606.

Dr. Ralf Paus (Manchester University)

Dr. Nathan Hawkshaw (Right) (clinicadelpelo.com)

The Next Step

After the initial wave of articles on the WAY-316606 discovery faded out, us dedicated hair seekers still had a question on our minds. When and how is this drug going to be trialed on humans? The airwaves were silent. Until now.

This latest follow-up Guardian article declares that Italian pharmaceutical company Giuliani is working to get WAY-316606 into human trials. Bravo. These Italian companies seem to take a bit of initiative when it comes to hair growth research. The Guardian article “How close is a cure for baldness?” also mentions RiverTown Therapeutics and describes them as “exploring a similar avenue with their drug RT1640.” Another tidbit was added after the mention of RiverTown and we can say the writer was 100% accurate: “it’s fair to say that whoever gets there first will make a lot of money.” 😉

59 Comments

  1. Ahmed bekeer on September 2, 2018 at 11:04 pm

    I trust that this is the best treatment for baldness treatment



    • Wallie G Breig on October 23, 2018 at 6:38 pm

      How do I participate in a Way 316606 study conducted by mail or in a US setting.
      Barbara L Breig
      6070 Anchor Point
      Perryville, Missouri 63775
      1-314-573-1072
      Walbar1@att.net



      • Follicle Thought on October 23, 2018 at 7:36 pm

        Hi Wallie, you’d have to contact the Guiliani company conducting the trial (which is based in Italy) to even be considered. I can remove your personal info if you’d like.



  2. Fahad on September 3, 2018 at 3:22 am

    This site really gives me hope
    Can you plz try to contact medipost and ask for an update ?



    • Follicle Thought on September 3, 2018 at 1:53 pm

      Medipost is doing fine. They said the product would likely be launched in Q4 or Q1 2019 and that is still the case.



  3. Hope on September 3, 2018 at 7:19 am

    I thought this was just discovered the the other day? I’m happy to hear they are starting human trials already. This is great news!



    • Follicle Thought on September 3, 2018 at 1:53 pm

      They’re working on it, the article says. We hope to hear the trials will begin soon.



      • Benny Greene on January 1, 2020 at 12:12 am

        sounds promising.



  4. Dean Jones on September 3, 2018 at 8:50 am

    Apparently this company is a privately owned company. No chance to buy any shares… -:(
    In any case, if they find a cure it will make many people happy!



    • Benny Greene on January 1, 2020 at 12:14 am

      Will pmg research be involved?



      • Follicle Thought on January 3, 2020 at 11:26 am

        Benny, why do you mention pmg research, how are they related?



  5. Moize on September 3, 2018 at 1:03 pm

    One thing that bothers me is why dr. Hawkshaw is no longer part of the development of the drug



    • Follicle Thought on September 3, 2018 at 2:29 pm

      Ok. That is because he’s licensed it over to Guiliani to develop.



  6. Edgar on September 3, 2018 at 1:06 pm

    Hello admin, how long for this to hit the market?



    • Follicle Thought on September 3, 2018 at 1:55 pm

      If it’s going the clinical drug route, anywhere from 5-7 years I’d say.



  7. Matthew on September 3, 2018 at 6:01 pm

    Molto bene! On an unrelated note, Histogen gave their decades old puke green shag carpet looking website a major facelift. Looks good!



  8. Adam on September 3, 2018 at 7:17 pm

    Is this drug supposedly a cure and will regrow hair which has been lost a while ago or is it meant to be potentially a treatment which will treat what we’ve already got?



    • Follicle Thought on September 3, 2018 at 7:57 pm

      Too far out to say, but CsA does have some powerful hair growth effects. If WAY was similar it could potentially regrow some lost hair.



  9. Sahar on September 3, 2018 at 11:52 pm

    Hi.Is this only for men?Or for women too ?And you think when it’s available?thanks



    • Follicle Thought on September 3, 2018 at 11:59 pm

      Thanks for reading. Should be for men and women. Don’t know exactly when, but years of trials left.



  10. Haartje on September 4, 2018 at 3:48 am

    This compound is already available via various webshops, right? Have people tried it already? Are there any good evaluations of guinea pigs available?



  11. Jarod on September 9, 2018 at 8:48 am

    Dear admin,
    I have read the original publication about WAY-316606 and I find something still concerning; all the hair follicles were taken from the back of the head of 40 patients. I feel it is unlikely those patients suffered from DUPA, hence we can assume that the hair follicles were all healthy and resistant to pattern baldness (be it caused by DHT or other factors). It doesn’t mean that WAY-316606 will necessarily be effective on a thinning hair. For instance castor oil is known for its hypertrichosis effect (topically or orally) and thus stimulates hair growth, but it remains kind of ineffective as a real solution to prevent thinning hair from falling. Although, the mode of action is quite different, it would have been interesting to have the same test performed on thinned hair. What do you think?



    • Follicle Thought on September 11, 2018 at 1:19 pm

      If the follicles were outside of the body they were in a comprised state and no longer deemed “healthy” in my opinion. But ultimately, for now I’ll let the researchers do their thing and hope that this gets into human trials and be thankful for that, and then check out their results in humans.



      • Swaraj Mohokar on November 19, 2018 at 8:40 am

        Isn’t there any progress? I really really need it, now more than ever



  12. Nikky yadav on September 26, 2018 at 5:02 pm

    Sir when updated this medicine from india..
    I hope boldnes free for world

    Way 316606 i’m waiting



  13. Swaraj on October 23, 2018 at 4:10 pm

    Will this drug grow back the widows peak which I’d acquired during androgenic alopecia?



  14. Patricia Duarte on November 7, 2018 at 11:43 am

    Great news. I’ve been checking for updates on this drug and also noticed that there was silence after the May wave of hopeful articles. Good luck to both parties and their new partnership.



    • Swaraj on November 14, 2018 at 12:29 pm

      Is there any progress?



  15. Niraj nimje on November 16, 2018 at 2:00 am

    Sir ise order kayse kre



  16. Denzel on November 19, 2018 at 10:35 pm

    Can I be in the first trial studies?



  17. Letty on November 29, 2018 at 6:47 pm

    I am a 63 year female with male-pattern baldness. Is way-316606 effective for my type of baldness ? And I thought I read where you said it would be out to public in Q1 or Q4 of 2019?



  18. Susan on December 9, 2018 at 9:24 am

    What osteoporosis drug currently includes the WAY-316606 ingredient?



    • Follicle Thought on December 9, 2018 at 10:08 pm

      Way-316606 is an osteoporosis drug itself that most likely did complete a clinical trial process.



  19. Callum Peach on January 9, 2019 at 11:59 am

    Any latest new regarding the progression for this drug to be available?



  20. sandesh on January 11, 2019 at 1:11 am

    HI SIR,
    WHEN THIS PRODUCT AVAILABLE IN MARKET FOR USE DESPERATELY LOOKING FOR IT. PLEASE KEEP UPDATED US,SO WE WOULDN’T SPEND OUR MONEY IN OTHERS TRAETMENT UNIL ITS READY.



  21. sandesh on January 14, 2019 at 11:50 pm

    DEAR Follicle Thought,

    ANY UPDATES ABOUT Way-316606.



    • Follicle Thought on January 15, 2019 at 1:13 am

      Hi Sandesh, no.

      As I’ve stated many times, to many people, if there was an update about any particular product/company you would find said update in the Updates section, or you would notice a new article written. Just as a helpful sharing to you, I guess it would be about 1-3 years before we hear any meaningful update about WAY-316606 moving ahead in its trials, but hopefully other treatments coming out much sooner would be of interest to you. Thank you for reading and supporting Follicle Thought.



      • Sandesh on February 13, 2019 at 4:29 am

        I noticed in social media that onion juice is best remedy to regrow hair from bad patch.Is it correct.
        Please correct me if I am wrong.



  22. SRINIVAS on February 23, 2019 at 1:59 pm

    When I expected in India



  23. ashok behera on March 17, 2019 at 3:09 am

    hello sir
    when release this medicine WAY-316606
    when come it in market



  24. john on June 5, 2019 at 9:58 am

    there way-316606 in the Alibaba website is that save to buy



  25. Igor on July 18, 2019 at 11:46 am

    Hello!! What news about WAY??? Do not be silent please!!!



    • Follicle Thought on July 18, 2019 at 1:02 pm

      I’ve just reached out to the company yesterday, but I’m not sure if there will be a correspondence. I’m certainly hoping for one.



    • Follicle Thought on July 20, 2019 at 2:59 pm

      There is an update coming soon, thanks for asking.



      • ngassuras@hotmail.com on August 26, 2019 at 12:16 pm

        So is this update directly from the company wrt results and when does soon exactly mean weeks months ? Can you elaborate. Many people want this drug asap.



        • Follicle Thought on August 26, 2019 at 5:53 pm

          Hi thanks for your enthusiasm. The update will most likely come in the first few days of September. It will definitely come in September.



  26. Mohd Akram on July 31, 2019 at 11:43 am

    What is the cost of this medicine



  27. mark on September 1, 2019 at 1:31 am

    its September now cant wait! Announce any-day now if still on track



    • siddharth singh on September 6, 2019 at 10:58 am

      sir when this medicine launch



      • siddharth singh on September 6, 2019 at 10:59 am

        please tell me and plese launch in 2019 only i lost my hair almost



  28. siddharth singh on September 6, 2019 at 11:01 am

    sir please reply as soon possible when this medicine came



    • Follicle Thought on September 6, 2019 at 12:03 pm

      An update about this development will come in September, it is a good update. But, please be patient there is no chance you will miss the launch of the product. It will still take some time.



      • Nick Assiouras on September 6, 2019 at 1:06 pm

        As everyone can see this is a huge problem for many and affects lives negatively daily.all hope that not only will drug be effective and safe but most importantly for doctors and government regulators to quickly cut red tape and lengthy trial periods because of the need and the fact the drug went through trials before with a good safety record. It’s important these people expedite the release to consumers quickly. Life is short @!



        • Nick Assiouras on September 16, 2019 at 11:30 am

          Well mid Sept no WAY316 news yet. Did you mean the update was good.. like good news positive results with drug or just a detailed update. It’s hard to justify what was meaning of …good update.??



          • Follicle Thought on September 16, 2019 at 5:31 pm

            It’s a positive update for sure, thank you for your patience the update is coming soon.



  29. Swaraj Mohokar on October 2, 2019 at 6:25 am

    October here now.



  30. Nick Assiouras on November 4, 2019 at 12:17 am

    Hope way 316 analogues work and are released soon.. but.. some big questions.. first in the graph from hawks research it shows y growth in x days BUT how long did the hairs get past that date –did they grow longer like terminal normal hair?? Second these test follicles were they compromised by dht to vellus status?? Third does way 316 reverse dht affected follicles to normal status? Forth … what is relationship between dht and sfrp protein that way 316 interrupts BECAUSE is it dht or sfrp that causes the baldness. .. perhaps you can clarify the above or hopefully ask the manchester team these queries. One more thing has anyone using dutusteride find it more effective than finasteride .Thank you.



  31. Benny Greene on January 1, 2020 at 12:13 am

    does pmg research offer it?



  32. behnam on September 26, 2020 at 5:45 pm

    Hello.
    Has anyone ever bought and used the raw powder of the medicine from Alibaba store or from the manufacturers of this medicine?
    If anyone has ever used the raw powder of this medicine, please explain to our about the effect of this medicine on hair and the daily dose of oral consumption of this powder and the duration of its use and the best type of way-316606 and so on.



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