HaplnScience and Rise Technology: New Hair Growth Companies Q2 2021
In this article we will take a look at two new companies developing therapies for hair growth in 2021.
HaplnScience: Targeting The Cause Of Aging In Hair Follicles
HaplnScience is a new company developing therapies for age-related diseases including androgenic alopecia, based where else, but South Korea. The company was founded in 2018 by experienced pharmaceutical executive Choi Hak-Bae and his scientist colleague Dr. Dae Kyong Kim. Their company seeks to create regenerative therapies by targeting the HAPLN1 protein. HAPLN1 stands for hyaluronan proteoglycan link protein 1. According to Hak-Bae, HAPLN1 plays an important role in tissue aging and can be used to “regenerate damaged tissue by acting on the extracellular matrix.” Currently, HaplnScience has four treatment indications listed in its pipeline: osteoarthritis, COPD, skin aging, and hair loss. Osteoarthritis is their most developed program nearing a phase 1 clinical trial in humans.
In a Korean article interview, CEO Choi Hak-Bae states his company’s skin and hair treatments will be jointly developed with partners. Though, he doesn’t specify whether partner companies are in place yet for those treatments (note to pharmaceutical companies reading this article). HS-301 is the codename for HaplnScience’s hair growth treatment which will be applicable to both men and women, and their website contains a bit of scientific rationale for the drug. In a nutshell, the company believes that HS-301 will be able to recapitulate hair growth by proliferating the human hair germinal matrix cells (HHGMC) at the base of the hair follicle. See image below.
HaplnScience.com – Click To Enlarge
The company has also proposed a mechanism of action (click the HS-301 tab) which involves rebooting the TGF-β and WNT/β-catenin signaling pathways. In various media quotations, CEO Choi Hak-Bae has iterated that HAPLN1 is a protein naturally found in the human body, thus, the safety aspect of this treatment should be a non-issue. Apparently, preclinical trials for HAPLN1 targeting osteoarthritis have gone well by regenerating cartilage in rats and goats. We certainly hope that HaplnScience secures the right strategic partner to move their interesting therapy for hair into preclinical/clinical trials immediately.
Rise Technology: UW Madison Hair Stimulation Cap Spin-Out
In other news, there is slow-but-steady progress coming from the lab of Dr. Xudong Wang of the University of Wisconsin at Madison. Back in September 2019, Wang’s research made headlines around the internet, as media outlets were quick to publicize the potential of a “baseball cap that could cure baldness.” The technology is based on a small “nanogenerator” device which fits inside of a cap and gathers energy from the movements of its user, and then transmits low frequency pulses of electricity into the scalp of the wearer. Below is a look at the proposed product on the new Rise website. Note that the device is not for sale yet.
risetechcom.wordpress.com
A decisive moment for this stimulation technology will be the upcoming human trial testing the device against androgenic alopecia. There is no date set yet, however, the trial is extremely likely to happen in 2021 as it has already been delayed a year due to restrictions which have taken place over the past year. Look for an update on Follicle Thought directly from Rise Technology in the next several months regarding the initiation of a human trial.
Posted in Hair Growth Treatment, HaplnScience, Rise Technology
Thank to reader John Doe for the info tip.
I’m always happy to welcome new players to this game. The hair loss/hair growth treatment industry continues to swell which is nothing but a good thing.
Goddamn, just send me a hat and I’ll test it for you all summer free of charge. One question is would Rise need to go through three stages of clinical trials for their electro stimulation cap? Or could we maybe see this product this year?
They would not need to go through 3 stages of trials as the device would likely under a 510k regulation like a laser cap. However, conducting a trial and launching the product by the end of this year seems like a lofty goal. 2022 more likely for the product.
I’m an eternal optimist. Thanks again for the update. Hopefully Mane Biotech can get on track. Apparently their app was launching “soon” 6 months ago.
@Radula you can download from their LinkedIn , go to latest post’s comments there is a link but not much use without their device anyway it’s there
Fingers crossed Admin
I visited their website today. It appears that two new staff members have joined. A hardware and a software engineer
It appears they are moving ahead.
Maybe a race between Mane and Rise….
Thanks Admin…good news.
Am just wondering how Mane are progressing? A key person sadly left the company.
Mane seems to be doing just fine at the moment. I know some people have already beta-tested their app. Hopefully I’ll have something to share from them this year.
Man this is awesome! Cant wait to buy that hat to cure my hairloss. I have my credit card ready for them. Brand new tech right here guys. 2021 the future of laser electro caps to cure baldness. I’ll give them 5k for this if they can grow me 4 strands of hair. Mane is even better with their electro pulse treatment. This will totally work. All the years of waiting for the breakthrough hair loss cure and we just found it. Getting off the big 3 today.
Ya never know Mjones, this could actually work. I have more faith in this stuff than Tsjui who’s trying to raise money by standing on a street corner holding a “will give you hair for money” sign. Oh yea, don’t forget his new line of super duper cosmetic products with no scientific evidence, photos. 😉
Yoda, I start losing faith to Dr.Tsuji as I know a YouTuber sent him a several questions about his hair cloning, which is considered as an online interview. Yet, it’s been almost over one month since the questions are sent. The questions are not complicated and should be easy to answer if Tsuji really knows his cloning procedures. Yet, we still got nothing from him, this is definitely a red flag for people.
Hey man dr.Tsuji already answered the questions but the guy who is translating and is writing the responses in an email format needed to clarify some of the answers with Tsuji because he didn’t understand himself. You should watch hairliciously’s latest video on it.
On, I didn’t realize that, appreciate your updates! We’re hoping the answers could be released soon!
Yoda..electro therapy is a great treatment for muscles and tendon injuries. I have experienced it many times. Therefore I am cautiously optimistic that the technology may provide at least some maintenance. Full regrowth can’t be expected anyway as indicated by the developer. Time will tell. At least, easy to use…..
??
Hey Admin! I’ve been chatting to this guy who’s looking to come out with a Procyanidin B2 supplement for hair growth, there have been multiple clinical studies in procyanidin and it has a really positive results in regrown (I think one study showed an average of 150% regrowth). From what I gather it’s only high grade procyanidin which leads to any hair growth but it is extremely expensive to buy, paired with the fact that it’s not patentable has made it kinda clear why no pharmaceutical company has followed this path. From chatting to him it seems like they’ve found a more economical way of extracting Procyanidin B2 from pine bark, rather than apple skin, and are looking to launch a product with a mailing list opening up in a couple months. I’m not sure if this is snake oil, the only reason I’m not 100% pessimistic is the list of previous trials which have shown good results, if you’re interested let me know and I can try and get you guys in contact and maybe you could follow up seeing if it’s anything worth while or just more wishful thinking.Thanks!
Hi Jboy,
Best news I heard in the last two years. I take grape seed extract everyday and had amazing regrowth and I am maintaining after an aggressive onset, but it has not near the amount of procyanidin b2 as they used in the study (400mg). I tried to buy pure form of PB2 but it’s really expensive and sold only for research purposes, it is the closest thing we have of a cure and I am so happy with this. May I ask what is the company? Want to follow their work and be the first to use that product. I would be willing to test it for free for them, if they are looking for pre launch consumer reviews.
Hello lost piece, I wanted to know if you take the extract or apply it on the scalp? and the extract is homemade or an oil? sorry for my english, it’s not good! I am from Argentina
Hey Missing Piece,
I haven’t heard about a company name for them yet but I’m really glad you’re excited. In my opinion procyanidin B2 is very overlooked, if someone finds a way to cultivate it at a lower price point then I think it would be superior to any other treatments available now. I would also encourage you to take a look at this post made yesterday: https://www.reddit.com/r/tressless/comments/mx6ncc/the_theory_that_explains_everything_please_help/?utm_source=share&utm_medium=ios_app&utm_name=iossmf it’s a long read but incredibly interesting. It seems to explain why procyanidin is so effective and the underlying cause of hair loss which hasn’t been investigated yet. I really hope a biochemist test his hypothesis so we can see if it delivers any tangible results.
Hi Jboy, I emailed you but no response yet. I would be willing to talk to the owner of this new venture.
Hey admin, Sorry I didn’t reply, I used my spam email, try this one! They said they’d be happy to speak with you and explain their project, I’m just waiting for them to respond with their contact info, once I get it I’ll send it your way!
Hello off-topic question, but do you guys have any experience with MinoxidilMax company? Is it legit, because their topical finasteride products look very appealing and am wondering if they actually work. Thank you in advance!
Yoda anything is possible but feel it’s a money grab. Plus, electrocurrents would prob cause shock to the scalp and make your hair fall out. Just my thoughts. We can do our own electrocap at home. Put a baseball cap on with foil under it and stick our fingers in a socket haha instant voltage for follicle stimulation lol. I’m hoping for some positive results from SM aka biosplice.
You could be right MJ, mainly I was using your comments to air my thoughts on being puzzled by so many still currently infatuated with Tsuji. Given that he’s unable to raise money from credible institutions and is begging the public, I just don’t get it. This along with his line of cosmetic products and that he’s never conducted any human trials make me skeptical, to say the least. Not implying he should be written off 100% but I wouldn’t stake my hopes on his treatment, cure or whatever it is.
Triple hair site is updated for Therapy 16 – ‘PROJECTED RELEASE IN MAY 2021’.
May be I am late to see.
I don’t put much stock in treatments that are natural based like T-16. I’ll keep an open mind, my guess is that at best it would be a good adjunct treatment to add to the known medical treatments currently on the market. The fact that they are in development on a medical treatment makes me think they know this and are just trying to crank up the revenue machine as soon as they can.
Thank you Yoda for your advice.
They have TH-18 (natural ingredients with Minox). I think that could be better choice then.
There are several studies already out there on pub med etc on iontophoresis (mild electro therapy) treatment for MPB. Some of them successful, when combined with other topical stimulants.
There are products out there already that do exactly what’s mentioned in the post.
http://belalab.com/en/parche-iontoforesis-anticaida-capilar/
As someone who has used iontophoresis I can speak very highly of its successful treatment of various different ailments.
I even used it for a short time on my scalp to see if it would work, alas I only attempted to do it for month and saw no significant results, although it did ‘feel’ like my hair was becoming more ‘wiry’.
When used with minoxidil the iontophoresis improved the efficacy of Minoxidil.
https://pubmed.ncbi.nlm.nih.gov/23450524/
@ BearlyEagle where did you buy the Electro patch? Bela Lab only seems to cooperate with other companies.
I didn’t have that exact patch I just have an iontopherosis machine so I thought I would try it on my scalp for a while, who knows if it may work long term. There was another Korean study that I read before attempting it which had great success apparently however I can’t seem to find the link now. The only difference is they were using a natural topical solution that they did not list the ingredients of.
On a side note, this came out today and is very, very interesting and certainly worth a read although the author of the piece claims that hair does not grow back in transexuals, although we know it actually does.
https://old.reddit.com/r/tressless/comments/mx6ncc/the_theory_that_explains_everything_please_help/
Scroll down to the hair growth pics in here
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775114/
Anecdotally I only started losing my hair when I stopped taking broccoli sprouts and sulforaphane in 2015. Prior to this I was taking the supplement for upwards of 6 months.
(the new tsuji interview released today) if tsuji secures funding this year or next it will be released by 2024 he said it would take a year for a 10 person human trial to be finished and then commercialization by 2024, I’ve been saying that for along time most people would disagree with me that’s fine we will see who’s right 🙂
Woofy, the timeline you said is just the best result if everything goes right. Now I suspect dr.Tsuji can raise enough fundings within this year. And even if he can start clinical trial in next year(that’s a optimistic time i predict), there are more difficulties waiting ahead. Let’s cross finger for his successful but don’t rely on it. 2030s maybe is a reasonable decade for real thing happens.
If Tsuji said it, it must be true! I heard he’s going to start dancing in a G-string so his fan boy crushes can stick dollar bills in to help him raise money. Settle down Woofy! 😉
Tbh, in the video he says that the money needed to be raised is not just for the hair follicle duplication solution but for other organ regeneration studies as well.
I think this is just Riken looking for more funding so they can continue with research but not actually producing anything.
The fact that he hasn’t been able to secure the $4.8 million is quite concerning I would say.
That’s too logical BE, like a CEO of a company I worked for once said when we were running out of money, “don’t be constrained by reality”!
Woofy brother he’s gonna charge 250k +USD for the procedure if he will ever be successful, that’s pretty crazy if you ask me. What percentage of population can afford to spend that much money on aesthetic surgery? Also you can’t be sure those hair will last for the rest of your life because obviously we will be the first generation to use tsuji’s technology ( if ever ). I am pretty pessimistic after the video to be honest
Shia, I think your concerns to the Money is the last thing we need to worry about for cloning. If the hair cloning comes out in real world and works fine, more capital would be invested to this field. Thus, the price for cloning will gradually become affordable to public. The problem is, we can’t even get a solid timeline for hair cloning from Dr.Tsuji. He now doesn’t have funds to start clinical trials and even he got money, there is no guarantee human clinical trial will be successful. The things we can do is donating money if you are willing to do so and hope he or any researches who give hair cloning a try will not give up.
hi, shia i’m not that upset about how much it will cost i just care about it being a reality and working on a human, not in a lab/clinical trial setting anymore and an available option in the tool box for anyone who can afford it. but you know it would be nice if insurance covered this or a regular hair transplant…
Woofy, Woofy , Woofy…hasn’t any of Yoda’s wisdom sunk in yet son?
Yoda at the end of the day my thoughts are thoughts your thoughts are thoughts. I’m just expressing my thoughts on this topic I don’t see anything wrong with that lol. It may seem like a fantasy and I’m getting ahead of myself but they are just my thoughts. We all want one thing and that is a cure. I hope you understand
I understand Woofy my boy, you seem like a good kid. What troubles Yoda is wasting energy on something that is light years away and may never come. I’ve said it before to you, there are alternate versions of approved treatments that I’m certain would give you better results. However it’s up to you to research these. I’ve been doing that for over 30 years and still have a decent head of hair. Not perfect but nor my predisposed destiny to be a NW 7 by this stage in life.
Keep the dream alive Woofy, it’s a step in achieving it someday. Do the things you can, big or small, to help make it happen. I think Yoda’s main concern is that you’re aware of your current options and risks, which I’m pretty sure you are. There are definitely many people who are in the boat of needing something beyond what’s currently available. In fact, whether a necessity or not, everyone on this site wants something beyond what’s currently available.
Tsuji is going to be having a 24 hour telethon to raise money for his treatment, cure or whatever it is. If you donate $250K you get the 1st procedure, a lifetimes supply of his new whiz bang cosmetic hair tonic and a free tote bag!
yoda lol, that’s Comedy gold
Yoda can be a douchebag but he is freakin funny! 🙂
BearleEagle….did you use the polyphenol apple vitamins from that study? Little confused on your post. Those results in that study are quite impressive.
Woofy- 4 person trial for cloning from tsuji is a joke and not large enough to prove it’s safe or side effect free. Plus it just sounds like a research study and not a true clinical trial. Cloning is decade away from even being discussed as a potential treatment. It’s just a marketing money grabbing ploy and mouse study as of now. One day it will happen but not yet my friend.
@MJones,
No I didn’t use the polyphenol apple vitamins, but contained in the link that I sent prior to that study hypothesises that perhaps the way we have been looking at stopping hairloss/ regrowing it is wrong. And I think he has a very intriguing point.
The natural flavonoid Procyanidin B2 has been shown to be extremely effective as per that apple study, however, why do we suddenly need to inhibit the production of DHT on our scalps in order to stop the follicle being attacked?
What has changed in our bodies that now makes the follicle susceptible to DHT?
The hypothesis states that perhaps there is another chemical sulforaphane present in our bodies which depletes or stops being produced which has a benefit of metabolising our DHT to stop it attacking the follicle, thus making DHT bind to the follicle starving it of nutrients.
I was saying that in my own experience I did not experience any hair loss (all of the male members of my family have glorious heads of hair, and the women too hue hue), until five years ago when I stopped taking a supplement called sulforaphane and eating tons of broccoli sprouts. Did my body become used to having a supply of sulforaphane from an external source and so stopped creating its own?
The apple study was merely to show that perhaps we should not rule out a “natural” treatment to this.
I know we should trust the science but I can personally vouch for having cured many ailments with natural alternatives and I think to be snobby about such things or to deride them simply as hippy nonsense might be doing ourselves (and our hair) a disservice.
Aside from rubbing green smoothies on our scalps and masticating broccoli sprouts all day, there must be a solution that can test out this hypothesis?
Anyways, there is a guy releasing the Procynadin B2 compound supplement in a couple of months.
Please see here….
https://www.reddit.com/r/tressless/comments/jesv0j/results_of_procyanidin_b2_in_clinical_studies/?utm_source=reddit&utm_medium=usertext&utm_name=tressless&utm_content=t1_gvp3rom
Admon what abbout triple hair?
They were supposed to release their product in May
Yes, Vlmp, I think everything is going fine for them. Product will still likely be launched next month. I will share the news and a brief update on them in May.
If anyone cares, Yoda is moving to his next phase of transitioning off oral Dut to topical. I was alternating the two every other day for the past month. Will now go to oral on MWF and topical the other days. So far, I’ve not noticed any increased shedding. Another test, I’ve been rubbing the topical on my ears. Why you say? When effective Dut/Fin slows to loss on your head and impedes body hair growth. In my most effective years on oral this was true but I’ve seen an increase of ear hair (old man alert!) the past couple years. The topical seems to be limiting the growth of hair on/in my ears which will be a positive sign. I’ll do a month of this and then move to oral twice a week, then once a week. Eventually the pan is to do away with oral all together and maybe even cut back on the .05% topical Dut , the 7% minox I use at night has .01% Dut in it, who knows maybe that’s enough.
excellent yoda let us know how you are going ahead to follow in your footsteps
Dear Yoda,
May I ask why you are dropping oral Dut if you’ve had such success and absence of sides on it? Wouldn’t oral be the most efficient way to inhibit DHT in the entire scalp?
Hi Tony, sure you can ask, good question! You are correct, I have no appreciable sides on oral Dut and Fin before. However, I have some brain fog that has gotten worse over the years. Is this due to oral fin/dut? We don’t know, my doctor is suspect. In any event, my doctor (urologist) said there no medical reason for me to take Dut (e.g. prostrate) and that it’s always preferred to get off oral meds if possible. I’ve read some good things about topical dut so thought I’d give it a whirl. Mind you, I’ve been on topical fin (along with oral) mixed in with minox for years and feel it did very little. Will be interesting to see how topical dut does, if I loose any ground I’ll be back on oral dut liceity split! Mind you, I still plan to continue oral minox along with am/pm topical applications.
ostrich eggs from a company called max world. Some of the before and after pictures show improvement from some very old people
any news on follicabio or samumed ?
I’ve been reading some of those theories on hairloss (mentioned in one of the posts above), and I think they are fascinating. If’ I’m reading them correctly:
-Hairloss could potentially be treated with Oral Procyanidin B2. One study showed 125% regrowth in 250 AGA patients, with zero side-effects.
-Hairloss might be linked to a decrease – or lack of – 3 alpha hydroxysteroid dehydrogenase. In order to get significant regrowth, you need to increase 3 alpha. Interestingly, my thinning began when I started Accutane, years ago, which reduces 3 alpha.
-The problem might not be DHT. The problem might be the fact that DHT isn’t being converted into Androstenol, or that it doesn’t convert in the right way.
-3 Alpha is altered and decreased by stress – especially chronic stress – or depression, and 3 Alpha normalises after anti-depressant pharmacotherapy with selective serotonin re-uptake inhibitors (SSRIs). Stress causes corticosterone which suppresses the production of a protein called GAS6, and leads to hairloss.
-In one test, it was found that 100% of patients with a certain type of dental malocclusion (Type 2 I think) had hairloss. Apparently, the malocclusion restricts bloodflow to the scalp. I’ve contacted my dentist to see if they can confirm.
All of this leads me to certain questions:
QUESTIONS
-How to get Oral Procyanidin B2?
-How to boost 3 Alpha… ?
-Is there any way to measuring 3 Alpha?
-Is there a way to measure androestadinol?
-Could Sulforaphane be used to increase 3 alpha? If so, what
would be a suitable method?
-Could anti-depressant pharmacotherapy with selective serotonin re-uptake inhibitors (whatever they are? tablets?) be used to lower stress / depression, and subsequently, hopefully, increase 3 Alpha?
-How to check corticosterone and GAS6 levels?
Paul how do you know that Accutane reduces 3 alpha hydroxysteroid dehydrogenase ? Link please ? I took Accutane myself. Thanks !
belgianboy, I’ve read that a few times. Most recently, I saw it in the long, detailed hairloss theory that is currently doing the rounds.
I don’t know if admin will want me to share the actual link, but if you search “tressless the theory that explains everything” you’ll find it.
Apparently, the theory has since been “debunked” by the all-knowing Kevin Mann, but I think its interesting and worth looking into. After all, isn’t that why all of us come to sites like this? For some hope and the potential of something that might improve our lives?
I’ve passed these theories on to a few people, and I’m going to try the B2 product when it arrives. Will it make a noticeable improvement to my hair? Probably not. But who knows? Worth trying something while we wait for cloning or a treatment that brings significant improvement.
I don’t mind you sharing links to Reddit, Paul.
I don’t want to get too off topic here but KMann can be condensed into 1) DHT causes hairloss and 2) PFS doesn’t exist and therefore every man with AGA should take finasteride without fear of consequences.
Triple hair TH16 won’t be out next month , they changed releasing date from May to just 2021 no date or month Hope they have some genuine reasons and good ones
https://vimeo.com/user123880895
good news from stemson
On I just saw the video, never mind my questions.
al.budny, what’s the news from them? The link you shared doesn’t have contexts in it? Could you please summarize the article you saw? Thank you!
pig trial was sucessfull
What’s the news, Al.budny? Only finding old videos
Where is the news link? I watched these videos but the most recent one was released 4 months ago
(Procyanidin B2 debunked) https://www.youtube.com/watch?v=uJpeHKKGd74
Good morning, I have a question that I would like experts on this subject as teacher yoda or administrator to help me clarify, I am very optimistic about the hair issue but I must also be honest in giving my opinion and asking why? Famous millionaires, politicians, artists, businessmen, and there are thousands of them, have no interest in investing in ambitious hair restoration or cloning projects, will their research indicate that a short-term cure is not within reach? I can give an example to Jeff Bezos, Dunald Trump, Joe Biden, Jhon Travolta, Bruce Willis they will not be interested in recovering their hair in exchange for any amount that they could pay without any problem and the only thing that remains the same as us is only finasteride and minoxidil?
please help me with this question thank you.
Yoda is very wise but does not have an answer to this question young Gooz. The only thing that pops into my mind is that if it were that easy everyone would be doing it. Something I learned years ago in my time in the medical device arena. This doesn’t mean that new treatments aren’t in reach but it isn’t easy. Think about it, the standard of care, Minoxidil and Finasteride, were found by accident. Companies have been trying to directly work on the problem and have either failed or just flat out are taking longer than we hope. Keep positive but always research what is currently out there beyond the off the shelf options of Rogiane and Propecia.
Gooz, it would be almost suicidal to openly support hairloss research for the people you mentioned. Social media, the boulevard, the lefties etc would either mock them or accuse them of having false priorities. It could be that those people you mentioned are already financing hairloss research but they would never publicly admit to it.
In the end, and that is mainly overlooked…. that you are balding is a positive fact for all the people who are not balding. Because their social position improves relative to others.
Because its good when you have nice hair and all other men are balding in this nice cocktail.bar you are visiting.
Pure genius, I bet that will work to spur Admin to action Marit, maybe you can use the same tactic to will a cure! 😉
I wonder if Marit is interested in supporting the Patreon page? 😉
Gooz, somewhat off your question, I have something to add in relation to the number of comments I’ve seen discouraging tressless amateur science / home remedy natural experiments, by saying, ‘big pharma and research institutes have invested billions in finding a cure; if experts can’t solve this…’ etc. This impression of round-the-clock scientists or experts working on hair loss is simply not the reality.
This is a quote from Dr. Christiano:
“In my training, nobody had talked much about hair. I thought maybe the reason was because it had all been figured out. When I started digging, I saw the opposite was true.” […] “I suspect it’s because it’s seen as a “cosmetic” problem. It’s the life-threatening diseases that get priority — and money.”
And this is from a similar article:
“As a scientist, she figured there must be papers on the genetics of hair that would give her insight into what was happening to her, but there was virtually no literature to be found. How could that be? […] She quickly learned why there was so little progress on hair disorders. ‘Institutions wrote back to me saying, in essence, that hair loss was trivial, cosmetic, insignificant in comparison to AIDS and cancer.”
And Dr. Paus response when asked about a cure: “whether and when a “cure for baldness” will become available very much depends on how much serious research effort (=funding) is being invested into it; since that has been dismally insufficient, we are in for a long wait – until this situation changes (thereafter*, 1-2 decades sound like a reasonable guesstimate)”
* “thereafter” means 1-2 decades AFTER sufficient funding, assuming he ever gets what he would consider to be sufficient. Probably not.
Well where we are now:
Aclaris quit JAK inhibitors, the website for Rapunzel Bioscience expired a few years ago, and Christiano just got a grant relating to Psoriatic Disease. Hair loss on the National Institutes of Health Grant Database brings up ‘Hair cells for hearing loss’ not hair loss. In fact, I have found no grants for Androgenetic Alopecia. Closest was a Hair Biology Prostaglandin d2 grant c.2008 worth $126K to Dr. Garza mentored by Cotsarelis. Cotsarelis led to Follica. Follica founded in 2005 and is still stuck in FDA trials. Tsuji is stuck in proof-of-concept and begging for millions. Stemson could suffer the same fate as Rapunzel—Rapunzel had even created hair farms: ‘a grid of hairs that are patterned correctly and engineered so they can be transplanted back into that same patient’s scalp.’ What happened!?
Are there any scientists specializing in Male-Pattern Baldness? As Yoda said above, Minoxidil and Finasteride were accidental discoveries. This is true also of future treatments: Follicum was discovered while studying atherosclerosis. Breezula was studying Hormones and acne. Samumed reverse aging. My point is that if there is a dark horse in this fight, it is one or many of us. We seem to be the ones who care the most, by far!
Hi Admin,
Thanks for the updates.
Is there any news on stemson?
Hey Ad, check the comments above that from Albudny, he said the pid trial is successful.
their hiring a lab manager. 1 of 2 things will happen, only the rich will have hair for a long time. or the follicles die out during cloning. its 50/50.
Thanks, I watched the video, but I wonder why stemson hasn’t published or announced the results of the pig trial if it was successful. The COO of fortunis just states that pig trials were successful.
Admin, is it possible for you to ask the guys at Stemson a few questions regarding their progress and plans for clinical trials.
It’s maybe just too early to ask clinical trials from Stemson
honestly im saying F it. I’m gonna get a hair system in a month. ive used propecia and rogain for 5 years and its only getting worse. im getting this incredible pain under my scalp. it feels like my hair is being eaten alive. im not putting hope anymore. ill probably wear a system for 10 years and if a cure happens it happens. I actually had 300k to spend on tsuji. I was pinning my hopes on it. But you take whatever you can get in life.
Thanks for the updated pipeline in the “Updates” section admin, hard to keep these straight!
Thanks for mentioning it Yoda! I appreciate it.
I will also have an interesting article related to hair transplants to share by the end of the week for everyone. Cheers
Hi,
Just wanted to bring the latest from Follicum. Unfortunately, phase IIa did not demonstrate efficacy of FOL-005 against placebo. Press release here:
https://follicum.se/follicum-rapporterar-top-line-resultat-fran-fas-iia-studien-av-fol-005-vid-behandling-av-haravfall-alopeci/
Though many did not have great expectations for the peptide, the scientific endeavor and awareness that came with Follicum should be appreciated.
Let me remind you, its not all doom and gloom:
We will be and are seeing a surge in scientifically-backed hair rejuvenation attempts given the recent and significant shifts in how society interacts with beauty and technology (e.g. online dating, social-media influencers and streamers, kpop globalization). I wouldn’t be surprised if we see even more companies from south korea, the capital of cosmetics, and impossible beauty standards.
Regardless of success or phase, this is a really great sign.
Brewing in the pipelines, we have:
– Hair multiplication
– AR degraders and upgraded AR inhibitions
– Exploration of a promising and new pathway involving prolactin
– Better transplant techniques
– Wnt/B-catenin signal activator
– Shaving the old noggin after Kanye makes it trendy
– Even gene editing may be on the distant horizon
plus many more.
Finally, keep your ears peeled, much much more will come as COVID stabilizes!
P.S. Much love to admin.
Stemore also got renamed:
https://news.mt.co.kr/mtview.php?no=2021043009512468167
They haven’t fully updated their website yet but it’s called Epibiotech now and the managed to get their Series B goal of 8m USD which is nice enough.
Thanks for that share Maker.
Hey FT, so stemson apparently finished the pig trial. Can you please try and get an update on when they think they will begin human trials? Thanks
No matter what the results Woofy will put lipstick on a pig! 🙂
I will try sometime Woofy.
What’s your take on the low light therapy caps? Can’t tell if they work or perhaps do more harm than good
LLLT caps seem to provide marginal benefit to most people who use them. I don’t think they make a true difference in most people’s experiences one way or the other.