Histogen And Replicel Coming To A Theater Near You

December 3, 2015 /
Posted on December 3, 2015

Okay, they probably won’t be at a theater near you, more likely a dermatologist’s office, but still…they’re coming.

Lee Buckler of Replicel and Gail Naughton of Histogen had some great updates to share with the world at the 2015 World Congress for Hair Research in Miami, Florida. The most important of the updates were the announcements that both companies should have a hair regeneration product on the market sometime around early 2018. Histogen may be sooner.

Lee Buckler’s Interview on Replicel

Gail Naughton’s interview on Histogen

This is exceptional news. Lee announced that Shiseido will be initiating their clinical trial for approval in Japan within a matter of weeks, and most likely, before the end of 2015. Then, when all goes well in that one trial, Shiseido will be able to offer the treatment commercially while they still continue the phases of the trial process. Gail Naughton mentioned that Histogen is finalizing a partner in Mexico, where Histogen could go right into a phase 3 trial. That trial could happen sometime in January 2016, and if the trial goes well, Histogen will be able to offer the treatment in Mexico. Having Histogen available in Mexico would be very convenient for those living in the US.

Follicle Thoughts

Hearing that Histogen and Replicel could potentially both be available to the public within two years from now is amazing news. It brings a great joy and a sense of relief. I believe strongly in both of these treatments. I feel that, of the two, the visual evidence I’ve seen from Histogen has been more impressive thus far. Though, when I hear the team from Replicel speak about their technology, it sounds to me that they believe they have a superior technology for growing hair follicles. I’m excited to see results from Replicel’s trials.

It’s interesting to imagine the possibilities of the treatments and how they might work together. At first, everyone will be learning the best protocols. Do we space out the injections over a period of 5 weeks? Do we use Histogen and then Replicel, or Replicel first? Can we combine the treatments in the same injection? Then over time, the hair transplant surgeons and the companies themselves will know much more about how the products work and the optimal ways to use them.

Is this a “cure”? – I think it’s just about everything we’ve hoped for right now, a way to grow hair through simple injections. Histogen’s product is so simple you only need to step into the office and get injected and be our your merry way. Replicel’s product requires a small sample of your scalp hair to replicate cells from. As far as it being a cure for everyone, it just might be, although for some it may be a longer process. Here’s a thought. If you use one or both treatments on your scalp, you’re basically guaranteed to grow some cosmetically significant hair. If necessary, you can couple these treatments with a hair transplant; a conservative number of grafts for someone using a large portion of their donor might be 3,500 grafts. 3,500 grafts + Replicel + Histogen would produce a meaningful result for anyone. Then, we can now think about injecting Histogen & Replicel into the donor where the 3,500 grafts were taken from to regenerate those follicles. Obviously, we have not seen results from this kind of protocol so far, but one would imagine it would work efficiently. So, now with Histogen & Replicel we are peering into the realm of unlimited donor.

Here’s the kicker: there are still several other companies bringing some amazing hair tech to the world as well, in due time. My favorites among them: Follicum, Rapunzel, and Theracell.

Enjoy

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17 Comments

  1. Ruh on December 3, 2015 at 11:25 am

    Dear Admin, thanks for the great post. I hope we’ll get the unlimited donor area for extreme Norwood level patients as their donor area is so limited for HT. I just want to know, is it really possible to regrow hair in donor area for multiple times with replicel ?



    • Follicle Thought on December 3, 2015 at 5:31 pm

      Hello Ruh,

      Thanks for your question. While I cannot say for sure that Replicel will grow hair in the donor multiple times because I have not done the experiments myself, I believe it is highly likely for several reasons. New injections of dermal sheath cells are new injections of dermal sheath cells. Logically, if new cells are injected then new hair will form. Also, the donor has historically shown conduciveness to follicle regeneration. We know that follicle regeneration is possible even now, in moderate amounts through the use of Acell.



  2. darkprince on December 3, 2015 at 3:42 pm

    Dr. Christiano has just been granted a patent for jak inhibitors ….Admin have a look ..

    http://patents.justia.com/patent/9198911



  3. Barthes on December 4, 2015 at 1:13 am

    I want to just say thank you Admin for your efforts with this blog. There are few pages about alopecia where I come on daily basis and this is one of them.
    Actually I am NW 2,5, 21 years old, it begun at slowly at 17. I was considering taking finasteride, but I know that I wouldn’t feel comfortable taking such a dangereous drug for a long time. That is why I am looking for all the news in the hair loss research and Histogen with Replicel seem to be the most promissing ones because they are just about 3 years away. Actually I don’t do anything with my hair loss apart from taking supplements and using Nizoral 2/week. Minoxidil did nothing for me, problably it only made my situation worse. I really hope that in 3 years when I will be terrible NW 4 or something, I will be able to end this cauchemar with HT&Replicel&Histogen, without terrible drugs. Finally the companies are on the right way to save us from that nightmare.
    Admin, I have a question: do you have any news about Rapunzel by Christiano? Last year in the article in NYT she said that in about two years trials would be possible.



    • Follicle Thought on December 4, 2015 at 1:38 am

      Hi Barthes,

      Thanks very much for your comment, I appreciate it.
      In regards to Rapunzel, no I do not have any news on it for the time being. Of course when I do I will be creating a blog post for it. Keep up your efforts to maintain healthy hair and you will be in a great place by the time Replicel and Histogen are released. All the best to you.

      Joseph



  4. lee on July 6, 2016 at 11:58 am

    admin, you can tell me how long setipiprant, histogen, replicel available on the market today? please !!



    • Follicle Thought on July 6, 2016 at 4:11 pm

      You’re looking at roughly 2 more years before the arrival of any of those.



  5. tom on March 22, 2017 at 7:27 pm

    Admin, would you be so kind as to contact histogen for an update? Thanks



    • Follicle Thought on March 22, 2017 at 9:55 pm

      Tom,
      Will try for an update as soon as possible. Thanks



      • tom on March 23, 2017 at 2:20 pm

        Thanks admin. We appreciate it.



    • vas on July 1, 2017 at 3:09 am

      hello,

      i have the same request. if possible please contact histogen for updates.
      fingers crossed.



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