Fukuda Lab TrichoSeeds Co. Hair Cloning Clinical Trial Update
TrichoSeeds Co., a biotech founded by Junji Fukuda PhD, has announced a timeline for the start of its hair cloning clinical trial.
ko-karei.com
Note, the snippet above taken from the ko-karie.com website has been edited since the publishing of this article. Luckily, we caught a screenshot of it before the change was made. The original snippet contained the latest relevant information about TrichoSeeds Co. and its plans to begin clinical trials. This revelation comes from the website of the 5th Healthcare Venture Award event, which takes place in Tokyo, Japan at the Nihonbashi Life Science Hub on October 27, 2023, and will be broadcasted online. The event is co-sponsored by the Japan Anti-Aging Association, and TrichoSeeds Co. will be one of five finalists competing for the event’s top prize. Other finalist companies involved in the competition include a startup aimed at creating drugs for autophagy which help with cellular regeneration, and a company developing epigenomic age measurement technology for Japanese people.
New information announced by TrichoSeeds Co. in September 2023:
- There are three confirmed candidate therapies for hair regeneration in TrichoSeeds’ pipeline. (Exciting news) These therapies are iterations of hair cloning using human cells. Described only as lines of research in a previous interview, one method involves injecting a single type of cells which signal for hair regeneration, the second method involves transplanting cell tissue which contains a mixture of cell types for to create hair follicle formation, and the third method is to create individual hair follicles “seedlings” grown in the lab for transplantation.
- Rohto pharmaceutical company and TrichoSeeds Co. will receive approval to begin clinical trials by the end of 2024.
Hair Cloning Trials Could Begin In 2024
This is all very favorable news, and in some ways, it can seem incredible. I’m happy to share this news, and also, I’d like to remind everyone that these statements by TrichoSeeds Co. are only a forecast. We absolutely would love to see a hair cloning trial begin next year, and we also know that that estimates are not guarantees. With that said, enjoy the news. We are fortunate to have so many different groups working on alleviating the condition of common hair loss. It would seem likely that the first trial with Rohto Pharmaceutical is a trial involving the most simple version for hair regeneration, the multiplied single cells. But, we will know more as time goes on. Hopefully, TrichoSeeds Co. will launch a website soon which will shed more light on its research and candidate therapies.
Please feel free to share this news with your hair-enthusiast friends. Citations are much appreciated when sharing. Let’s hear from the readers in the comments section below.
Posted in Hair Cloning, Hair Growth Treatment, TrichoSeeds Co.
Special thanks to “Johnson” for the news tip. And Herbert from HairDAO for linking to the Top-Researchers interview article where the featured image was sourced from. It appears the 3 pipeline candidates were described previously as research lines and the article has been updated.
Please also see my previous article with an older interview with Junji Fukuda PhD: https://folliclethought.com/fukuda-lab-yokohama-university-cloning-update/
Before this news was released, I also heard from Junji this month and he briefly shared that his startup had partnered with a pharmaceutical company to begin clinical trials.
Sorry FT but could you briefly describe the process of this hair regeneration I still don’t seem to understand how this all works? Thanks
YoYo, it would appear that the first iteration from TrichoSeeds will be an injection of a cloned/multiplied type of stem cell to create hair regeneration. There are other planned techniques which involve culturing a mixture of hair follicle cells before implantation, and the final method is to create hair follicle “seedlings” for transplantation.
Here is a quote from Junji about this:
“Actually, the third method of growing hair outside the body was something I had never imagined at first. A student happened to discover this while creating the second “hair seed” (as we call it), the “hair follicle primordium.” Normally, after three days of culturing, the cells would turn into seeds, so we immediately transplanted the “seeds” onto the backs of animals to test whether they could produce hair. When the student left the seed for three days without transplanting it, when he looked at it under a microscope, he noticed that something had grown from the seed. When a pathologist immediately examined it, it was discovered that it had a structure similar to that of hair, and this third method of creating “hair seedlings” was born. However, at first it was a very inefficient method, with only one growing for every 300 produced. In our 2022 announcement, we reported that we had increased this efficiency to nearly 100%.”
Thank you so much FT!
Thanks for the good news admin 🙂 Stay optimistic for the future
Thanks Nobody! By the way, I saw you commented multiple times, comments need to go through moderation before they are approved. That is the reason you didn’t see it immediately.
No news here actually.
The 3 candidates have been announced and explained by Fukuda a couple of months ago.
You are writing „by the end of 2024“, but that’s nowhere in the link or snippet. It says „by next year“. I don’t know why you are skewing that, seems odd to me.
Also the „pharmaceutical company“ is Rotho Pharma.
Ben, the news is that an updated timeline of “by next year” aka by the end of 2024 for trial initiation has been announced. This was not previously announced, its always “in the next few years, etc.”
I’m confused at what you mean by skewing? As of today, we are in the year 2023, next year is 2024. If a company says they are going to be approved to enter a trial “By next year” that means by the end of the following year. He certainly does not mean by the end of 2023/start of 2024. To be frank, I can’t understand why my assessment seems odd to you.
Anyone else please feel free to chime in. Does anyone else have the assumption that trials would begin by the start of 2024? No way in my opinion.
No prob, Ben. If you don’t enjoy the content here you can seek elsewhere 🙂
It’s obvious that if a company says “they will get permission to start trials at X time” then they absolutely are intending to begin the trials then. I’m not pessimistic, just realistic, and I also know what I’m talking about. You sound like you just want to complain, and that’s ok, you can, just not here.
If they had meant “by the end of this year”, that is what they would have said, when they invoke “next year” it’s because they are intending for it to happen next year. I don’t believe your comment was a correction. But, you are right that it is my blog, Ben, and I allow people who appreciate the content to interact here. If you want to be a respectful participant, you can interact here as well. Until then, peace 🙂
When will it really be coming out…im.so ready to get it done….
Hey FT compared to your thoughts in 2020 how do you view the landscape of hair loss let’s say in the next 3-5 years.
First off, it’s hard for me to remember the year 2020 exactly, but I remember there was some hype around Tsuji at the time which has since evaporated and now recently resurged a bit. With all the names of TrichoSeeds, Epibiotech, Stemson, OrganTech (making a comeback), and a longer list of drugs in the pipeline, things look like at least a small improvement over 202, YoYo. Still some work to be done. Results from Technoderma Medicines will be important, as well as GT20029 phase 2.
I agree with you as well, I feel like 2026/2027 will be pivotal as there is a possibility that Epibiotech or AMP-303 may come to fruition which would be a game changer for us all.
And you did forget to mention dNOVO however they have been quiet since 2021 which isn’t exactly reassuring (so far) lol
And btw did you hear about this? https://www.thebrighterside.news/post/groundbreaking-treatment-can-regenerate-90-of-lost-hair-study-finds
Yes, thanks, I have heard of that. It’s actually a bit of an older study YoYo. I had an article about the startup attached to it, but it looks like Ke Cheng has abandoned that project and is focusing on cancer drugs lately. https://folliclethought.com/exosomes-therapies-for-hair-loss/
Dear Admin, thank you so much for the hopeful news!
Do you have news from Angela Christiano or Colin Jahoda?
Hairfollicles cells are immunoprevilegated so an allogenic transplantation should work.
I know from a doctor who had transplanted some hair from mother to sun and it worked without taking immunsupplesiva.
Thanks Ingrid. No news from Christiano or Jahoda at the moment.
Thank you admin for the great news!
Are there news from hairtranplant to another person?
Hair follicels are immunoprevigelated and it should work.
I know a doctor who transplanted some follicles from mother to sun and it worked.
Thanks, I don’t believe that immunopriveliged hair transplants will become common. I think more companies would rather focus on creating cloned cells or follicles. The Korean researcher is probably the best candidate to try to market that procedure.
Hi FT,
What do you think of recently published research that indicates that malloclusion type 2 might be the cause of hairloss?
https://reddit.com/r/HairlossResearch/s/HicR5GAui2
Dirk, at first glance I don’t see much there. Perhaps there are some correlations that do exist, and some usefulness to study the theory more in depth, but I’m just respectfully not sold on the totality of the concept for now. Maybe it represents a piece of the puzzle? Respect to the doctor for presenting something.
Sorry about the double email notification! Only one post was created, the Update triggered an unintended email notification.
This looks fantastic. I think this is what everybody is waiting for.
Any information, first estimation, or even opinion about the future cost of such procedures? Can we expect something “reasonable” as in around the upper scale of current hair transplant procedures? Or is it simply too early to make any projection?
Fuwala, we’ll need to know a bit more about what the procedure entails to make a better estimate. I think an estimate around a moderate-larger hair transplant procedure is a fair estimate. Like you say, it may be a bit early to make a prediction.
I heard of Alma Ted Laser for hair growth. Do u know anything about this company?
I’ve heard of Alma before, haven’t heard of many prevalent hair transplant doctors adopting the technology yet.
Pelage Pharmaceuticals news coming soon, according to the grapevine.
I’m gonna guess the initiation of clinical trials next, it’s the only news left from them 😉
The recent Dr. Bloxham Verteporfin study post has been updated with a Q&A with Dr. Bloxham.
https://www.linkedin.com/feed/update/urn:li:activity:7115001747886014464/ Stemson is going to present their progress in this conference
Thanks for sharing YoYo. I’ll see if the presentation is available online.
Hey FT have you got any updates on dNOVO? It’s a little strange that they’ve stopped giving updates on the company for over 2 years now, hopefully they’re still in R&D
YoYo, I have not received any updates from the company directly, which is not promising. I contacted them to get feedback on a rumor about their current active status. They did not follow up with me, which doesn’t bode well for the rumor, I suppose.
Understandable not every company are going to be successful on their attempts. Thanks anyway FT!
dNovo is inactive in Ycombinator https://www.ycombinator.com/companies/dnovo
Great find Yogui, very appreciated. It appears the rumors are true about dNovo.
Hey FT,
What are your thoughts on Folix 22?
Thank you for all the work you put in.
Hi there, I could not see any ingredients listed on the website briefly, and I saw some really jaw-dropping results images on the website. In fact, I’d have to say some of the photos are a bit unbelievable – literally. Doesn’t quite add up at first glance.
Thank you for your insight
These two articles are interesting. We are living in a surprising time with a lot of science behind it.
https://www.science.org/doi/10.1126/sciadv.adg0297
https://www.science.org/doi/10.1126/scitranslmed.adf7547
Hey FT, is there any update coming from Pelage? Thanks!
YoYo, yes there will be a press release from Pelage. However, it’s up in the air when. I would be very surprised if it did not come by the end of October.
Perfect thanks again FT!
It looks like Triple Hair has received the investment it needed to move into their phase 3 clinical trial.
More at https://folliclethought.com/updates/
https://clinicaltrials.gov/study/NCT05324293?tab=results
Trial is completed (Hmi-115)
I had contact to Dr Hoffmann from Repicel.
They search men to test topical medcine against andronetic alopezia in Germany.
Sounds interesting Ingrid.
By the way, I know the news scene has been a bit quiet lately, but there are some new article stories coming soon. I’ve been doing my best behind the scenes.
It’s honestly like receiving mail in prison FT, keep ’em coming…
LJ, I’ve got a lot of new leads in the works. Doing my best to get something out to you guys soon!
Thanks, appreciate your work.
We you be watching the online Fukuda presentation on the 27th FT?
Yes, I will be YoYo. I would like to find a Japanese reader to help translate.
Is the online Fukuda presentation for everybody to see? Do you have the exakt time? You make good works FT!
Ingrid, yes the link to the event is in the article above. Exact time should be October 27, 2023 (Friday) 15:00-17:00. You may register through the link mentioned, many have done so.
Is this the time in Japan?
I believe it will be around 8am CET, Ingrid. You may register for the event and it shows the times.
It was not possible for me to see the event.
What are the news ?
I did not see the event. If anyone did, please share.
Did they start clinical trials on Humans? Is there any news from Fukuda Lab?