Pelage Pharma Gains New Injection of Funds to Progress into Phase 2
Positive news for Pelage Pharma as they close their Series A funding round.
Pelage Pharma is a regenerative medicine company developing a topical treatment called PP405 that is claimed to reactivate dormant hair follicle stem cells and trigger new hair growth. This treatment is aimed at people suffering from all types of hair loss. Pelage has raised $16.75 million, which will help the company progress to Phase 2 clinical trials following the completion of its first-in-human Phase 1 clinical trial. Google Ventures (GV) led the funding round with participation from Main Street Advisors, Visionary Ventures, and YK Bioventures.
PP405
During the initial clinical evaluation of PP405, Pelage’s indication for androgenetic alopecia and other hair loss conditions, it was observed that applying 0.05% of the product topically for seven days caused no adverse effects. This trial confirmed that the product was suitable for daily use. Additionally, this trial demonstrated that the product worked as expected by increasing a key marker for stem cell activation, which was in line with the anticipated mechanism of action identified in pre-clinical studies. These findings are scheduled for presentation at the upcoming American Academy of Dermatology meeting, which takes place on March 8-12 in San Diego, California.
We can expect Phase 2 trials to begin in mid-2024.
Reflections
Follicle Thought has covered Pelage Pharma news here and here. It is promising to see the advancements made by Pelage, and we look forward to seeing the results of the Phase 1 trial when they are presented at the AAD Annual Meeting. Several other companies also target or utilize stem cells in hair loss treatments. These include dNovo Bio, who work on stem cell regeneration (you can read about them here), Niostem, and Stemson Therapeutics.
Let us know what you think about this news in the comments.
Posted in Hair Growth Treatment
When will there be a new topical or other product out that people can try? Still seeing a lot of early stage products on here which are great. But it would be nice to see some things that will be released within a month or two or even 6 months? We’ve been hopeful about 2023 and 2024 products for a long time, but nothing seems to be getting released? Can someone please comment on what may be coming out in the very near future?
Couldn’t agree more Brian!
Don’t forget about niostem!
Absolutely! Will add them in!
Niostem look legit as team and innovation and even transparency but then they start giving the 6x better than fin and minox and share 3 months improvement pics that doesn’t really show that much of an improvement which makes me question them. Nevertheless mine should arrive end of April so lets see
Is there another thread for products which will be released soon? Know you provided an update on near term products last year?
There are mixed reviews on niostem Does it work? Has FT reviewed this product?
Their webinar today contained some interesting new info – https://niostem.webinargeek.com/webinar/replay/eT1ah9Ka5Fw3hCEDprqRyAN09hHC7AOi__PzHKdOM7U/
https://newatlas.com/science/keratin-gel-hairloss/
Hopefully some newd
Hey FT,
I got a long-ish question about this. Mind if I send in the “Contact” section? I assume that you’re a busy man and don’t want to waste too much of your time.
Either way your work here’s appreciated.
Yep, feel free to send it over!
It seems like there’s a disagreement about if stem cells are dormant or if they disappear completely. Is this true? Should we be able to see that somehow?
In many MtF trans people taking female hormones to transition, you see an impressive revival of “dead” hair follicles. This gives me hope that these follicles aren’t actually dead just very dormant.
Hello admin!
Is there any news about PP405? Thanks in advance 😀